Abstract
The virus of foot-and-mouth disease has 2 stable maxima: pH 3.0 and 7.6. A minimum lies at pH 6.0-6.5; the isoelectric point, at pH 3.5-3.9. The virus is probably bound to a colloid carrier, since its stability is influenced through binding to the carrier particle. The virus is injured, as shown by loss of activity, after repeated shifting between alkaline and acid conditions. The ampholyte behavior of the virus speaks for its protein nature.

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