Independent evolution of neurotoxin and flagellar genetic loci in proteolytic Clostridium botulinum
Open Access
- 1 January 2009
- journal article
- Published by Springer Nature in BMC Genomics
- Vol. 10 (1) , 115
- https://doi.org/10.1186/1471-2164-10-115
Abstract
Proteolytic Clostridium botulinum is the causative agent of botulism, a severe neuroparalytic illness. Given the severity of botulism, surprisingly little is known of the population structure, biology, phylogeny or evolution of C. botulinum. The recent determination of the genome sequence of C. botulinum has allowed comparative genomic indexing using a DNA microarray.Keywords
This publication has 49 references indexed in Scilit:
- Phylogenetic analysis of Clostridium botulinum type A by multi-locus sequence typingMicrobiology, 2008
- Survey of Genomic Diversity among Enterococcus faecalis Strains by Microarray-Based Comparative Genomic HybridizationApplied and Environmental Microbiology, 2007
- Bacillus subtilis Genome DiversityJournal of Bacteriology, 2007
- Flagellar glycosylation – a new component of the motility repertoire?Microbiology, 2006
- Sequence Variation within Botulinum Neurotoxin Serotypes Impacts Antibody Binding and NeutralizationInfection and Immunity, 2005
- Diversity of Proteolytic Clostridium botulinum Strains, Determined by a Pulsed-Field Gel Electrophoresis ApproachApplied and Environmental Microbiology, 2005
- Plasma membrane localization signals in the light chain of botulinum neurotoxinProceedings of the National Academy of Sciences, 2004
- Characterization of the Genes Encoding the Botulinum Neurotoxin Complex in a Strain of Clostridium botulinum Producing Type B and F NeurotoxinsCurrent Microbiology, 1998
- Phylogeny and taxonomy of the food-borne pathogen Clostridium botulinum and its neurotoxinsJournal of Applied Microbiology, 1998
- Mosaic Type of the Nontoxic–Nonhemaggulutinin Component Gene inClostridium botulinumType A Strain Isolated from Infant Botulism in JapanBiochemical and Biophysical Research Communications, 1996