Epstein–Barr Virus in Smooth-Muscle Tumors

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Abstract
Lee et al. (Jan. 5 issue)1 described three young liver-transplant recipients in whom smooth-muscle tumors containing the Epstein–Barr virus (EBV) genome developed. In the same issue of the Journal McClain et al. reported an association of EBV with leiomyosarcomas and leiomyomas in five children and one young man with AIDS.2 A causal relation between EBV infection and the subsequent proliferation of smooth-muscle cells was thought to be likely.3

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