Improved Intestinal Transport of PD 158473, an N-methyl-d-Aspartate (NMDA) Antagonist, by Involvement of Multiple Transporters
- 1 December 2002
- journal article
- research article
- Published by Elsevier in Journal of Pharmaceutical Sciences
- Vol. 91 (12) , 2579-2587
- https://doi.org/10.1002/jps.10241
Abstract
No abstract availableKeywords
This publication has 20 references indexed in Scilit:
- Evidence for Overlapping Substrate Specificity Between Large Neutral Amino Acid (LNAA) and Dipeptide (hPEPTl) Transporters for PD 158473, an NMDA AntagonistPharmaceutical Research, 1999
- Automated sample preparation for drugs in plasma using a solid-phase extraction workstationJournal of Pharmaceutical and Biomedical Analysis, 1998
- Uptake and transport of the ACE-inhibitor ceronapril (SQ 29852) by monolayers of human intestinal absorptive (Caco-2) cells in vitroInternational Journal of Pharmaceutics, 1996
- Potent, Orally Active, Competitive N-Methyl-D-aspartate (NMDA) Receptor Antagonists Are Substrates for a Neutral Amino Acid Uptake System in Chinese Hamster Ovary CellsJournal of Medicinal Chemistry, 1995
- Angiotensin‐converting enzyme (ACE) inhibitor transport in human intestinal epithelial (Caco‐2) cellsBritish Journal of Pharmacology, 1995
- Substrate specificity of the di/tripeptide transporter in human intestinal epithelia (Caco‐2): identification of substrates that undergo H+‐coupled absorptionBritish Journal of Pharmacology, 1994
- Uptake of the cephalosporin, cephalexin, by a dipeptide transport carrier in the human intestinal cell line, Caco-2Biochimica et Biophysica Acta (BBA) - Biomembranes, 1990
- Excitatory amino acid receptors in epilepsyTrends in Pharmacological Sciences, 1990
- Physiological and pathophysiological roles of excitatory amino acids during central nervous system developmentBrain Research Reviews, 1990
- Determination of intrinsic membrane transport parameters from perfused intestine experiments: A boundary layer approach to estimating the aqueous and unbiased membrane permeabilitiesJournal of Theoretical Biology, 1988