Synthesis of some A-Ring Steroidal Cyclopropanols

Abstract
The preparation of two epimeric secondary cyclosteroid alcohols in the steroidal A-ring by an intramolecular 1,3-elimination of bromide with zinc–copper couple is described. Iso merization of the endo-cyclopropanol to the exo-cyclopropanol is shown to occur with either the couple or zinc acetate. Solvolysis of the cyclopropyl tosylates is discussed. Spectral data are recorded.