Endogenous Creatinine Clearance as a Clinical Measure of Glomerular Filtration Rate
- 9 October 1971
- Vol. 4 (5779) , 84-86
- https://doi.org/10.1136/bmj.4.5779.84
Abstract
Endogenous creatinine clearance was assessed by inulin in 91 simultaneous studies in 41 patients and proved an accurate measurement of glomerular filtration rate. For filtration rates <20 ml/min the creatinine clearance may slightly overestimate the glomerular filtration rate. Successive determinations of filtration rate by either method may vary by 20% even though the methods agree with each other. Glomerular filtration rate itself is variable, and in its clinical usage this should be recognized.Keywords
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