Identification and characterization of normal length nonfluorescent Y chromosomes: cytogenetic analysis, Southern hybridization and non-isotopic in situ hybridization
- 1 October 1990
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 85 (6) , 569-575
- https://doi.org/10.1007/bf00193576
Abstract
In two female patients with a 45,X/46,X,+mar karyotype the marker chromosomes were identified as normal length nonfluorescent Y chromosomes (nlYnf) using non-isotopic in situ hybridization (NISH) complementary to routine cytogenetic analysis and Southern hybridization. The recognition of the nlYnf as isodicentric in both patients illustrates and confirms the usefulness and importance of NISH in the identification and characterization of this and many other types of complex chromosome rearrangements.This publication has 44 references indexed in Scilit:
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