Hybrid Virus−Polymer Materials. 1. Synthesis and Properties of PEG-Decorated Cowpea Mosaic Virus
- 27 March 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Biomacromolecules
- Vol. 4 (3) , 472-476
- https://doi.org/10.1021/bm025740+
Abstract
Cowpea mosaic virus was derivatized with poly(ethylene glycol) to give well-controlled loadings of polymer on the outer surface of the coat protein assembly. The resulting conjugates displayed altered densities and immunogenicities, consistent with the known chemical and biological properties of PEG. These studies make CPMV potentially useful as a tailored vehicle for drug delivery.Keywords
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