DEGRANULATION OF MAST CELLS IN PERIPHERAL NERVE INJURIES
- 1 July 1967
- journal article
- research article
- Published by Hindawi Limited in Acta Neurologica Scandinavica
- Vol. 43 (3) , 365-374
- https://doi.org/10.1111/j.1600-0404.1967.tb05739.x
Abstract
The early mast cell changes arising from peripheral nerve injuries of different degrees of severity were studied. In sectioned, crushed and compressed rat sciatic nerves, a rapid degranulation of epineurial, perineurial and endoneurial mast cells was observed at the site of the trauma, whereas mast cells in the distal endoneurium were not de-granulated. The mast cell products, heparin, histamine and 5-hydroxy-tryptamine are apparently liberated in the traumatized region of the nerves, where they can exert their actions on other structures in the nerves.This publication has 15 references indexed in Scilit:
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