HLA-A11–Associated Resistance to Skin Cancer in Renal-Transplant Recipients
- 8 November 1990
- journal article
- letter
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 323 (19) , 1350
- https://doi.org/10.1056/nejm199011083231914
Abstract
Renal-transplant recipients have a marked increase of viral warts, premalignant actinic keratoses, and skin cancers.1 , 2 Both cutaneous and cervical squamous-cell carcinomas are associated with human papillomavirus.3 4 5 We compared patients who had skin cancer potentially related to papillomavirus with nonimmunosuppressed patients, in whom there is a negative association between HLA-A11 and virus-related carcinoma of the cervix.6 We also investigated the HLA-associated susceptibility of renal-transplant recipients to skin cancer for other HLA alleles.Keywords
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