The Effect of Fluoride and Stannous Ions on Streptococcus mutans
- 1 January 1982
- journal article
- research article
- Published by S. Karger AG in Caries Research
- Vol. 16 (4) , 298-307
- https://doi.org/10.1159/000260612
Abstract
The effects of various salts of fluoride and tin were assessed on Streptococcus mutans NCTC 10449S viability, growth, acid production, glucan, DNA formation, and tin accumulation. SnF2 had more potent bacteriostatic and bactericidal effects than SnCl2, NaF, Na2SnF6 or TiF4. SnF2, SnCl2, Na2SnF6 and NaF (at 10 ppm F or Cl) reduced the growth yield of S. mutans, while acid production by this organism appeared to be reduced only in the fluoride-supplemented media. Bacterial growth in fluoride-supplemented media resulted in greater net amounts of both the water-soluble and alkali-soluble glucans per bacterial mass, with SnF2 having the greatest effect, increasing the water-soluble component 10 times and the alkali-soluble component 3 times over the controls. Greater tin uptake was noted by cells exposed to SnF2 than by those exposed to SnCl2.Keywords
This publication has 2 references indexed in Scilit:
- Phosphoenolpyruvate-dependent sucrose phosphotransferase activity in Streptococcus mutans NCTC 10449Infection and Immunity, 1979
- Permeability of the Envelopes of Staphylococcus aureus to some Salts, Amino Acids, and Non-ElectrolytesJournal of General Microbiology, 1959