2-Alkoxy-5-amino- and -5-arenesulphonamido-1,3,4-thiadiazoles and related compounds

Abstract
2-Alkoxy-5-amino-1,3,4-thiadiazoles are obtained by the action of cyanogen halides on alkoxythiocarbonylhydrazines, or by reaction of thiosemicarbazides with dialkoxymethylenimines. The latter process may also give 5-amino- or 5-alkoxy-1,2,4-triazole-3-thiols. Acylation of the aminothiadiazoles with arenesulphonyl chlorides gives 2-alkoxy-5-arenesulphonamido-1,3,4-thiadiazoles or 2-alkoxy-4-arenesulphonyl-5-arenesulphonylimino-4,5-dihydro-1,3,4-thiadiazoles.

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