Neurotoxic Effects of Glutamate
- 20 December 1973
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 289 (25) , 1374-1375
- https://doi.org/10.1056/nejm197312202892519
Abstract
To the Editor: In a recent article1 we stated that several animal species are susceptible to the neurotoxic effects of glutamate and related amino acids. In a simultaneously published editorial,2 Filer and Stegink commented that "the neurotoxic effects of these amino acids in species other than the mouse are debatable." By keeping open the debate, perhaps we can get out the facts on glutamate.Filer and Stegink invoke "a null effect that may be strain related" as their argument against susceptibility of the rat. We note that the "null effect" referred to was carefully explored by Burde et al.3 , 4 and . . .Keywords
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