The Antigenic Relationship of Strains of Trypanosoma brucei Isolated in Nigeria

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Abstract
The relationships of 11 strains of Trypanosoma brucie were determined by agglutination tests with antisera to the basic and predominant antigens of the strains to assess the relative values of these antigens for classification purposes, and the antigenic diversity of T. brucei in Nigeria. The indications of the antigenic relationships of the strains obtained by comparisons based on both types of antigens were very similar, but comparisons of predominant strain antigens were easier to make and were applicable to more strains than were comparisons of basic strain antigens. Clones prepared from 4 strains isolated in one place in Nigeria were antigenically related, but clones of 2 other strains from the same area were antigenically distinct. Six strains from widely separated localities were antigenically different and produced few antigens in common.

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