Schistosoma mansoni: Activity responses in vitro to praziquantel
- 1 June 1979
- journal article
- research article
- Published by Springer Nature in Zeitschrift Fur Parasitenkunde-Parasitology Research
- Vol. 58 (2) , 169-174
- https://doi.org/10.1007/bf01951341
Abstract
The effects of praziquantel, a novel antischistosomal compound, on the activity of adultSchistosoma mansoni (Liverpool strain) in vitro were investigated. Worm activity was modified at all concentrations of praziquantel. High concentrations (above 0.5 μg/ml) produced rapid paralysis, whilst low concentrations of praziquantel stimulated worm activity. It is concluded that such activity modification could lead to worm displacement in vivo.Keywords
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