Nonequilibrium Response Spectroscopy and the Molecular Kinetics of Proteins
- 12 January 1998
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review Letters
- Vol. 80 (2) , 401-404
- https://doi.org/10.1103/physrevlett.80.401
Abstract
Nonequilibrium response spectroscopy is a novel method of analyzing the molecular kinetics of voltage-sensitive proteins that involves measuring of the nonequilibrium response of the molecules to fluctuating fields with large amplitudes and frequencies. This response is exquisitely sensitive to features of the kinetics that are difficult or impossible to resolve by means of more traditional relaxation transient experiments.Keywords
This publication has 14 references indexed in Scilit:
- Nonequilibrium Response Spectroscopy of Voltage-Sensitive Ion Channel GatingBiophysical Journal, 1998
- Observable and hidden singular features of large fluctuations in nonequilibrium systemsPhysics Letters A, 1994
- Effect of focusing and caustics on exit phenomena in systems lacking detailed balancePhysical Review Letters, 1993
- A sodium channel gating model based on single channel, macroscopic ionic, and gating currents in the squid giant axonBiophysical Journal, 1991
- Single-channel, macroscopic, and gating currents from sodium channels in the squid giant axonBiophysical Journal, 1991
- Sodium current in voltage clamped internally perfused canine cardiac Purkinje cellsBiophysical Journal, 1987
- Noise Induced TransitionsPublished by Springer Nature ,1984
- Voltage-noise-induced transitions in electrically excitable membranesBiophysical Journal, 1981
- Fluctuations in Bistable Tunnel Diode CircuitsJournal of Applied Physics, 1962
- Studies on the axon membrane. I. A new methodJournal of Cellular and Comparative Physiology, 1949