Full Spectral GC/MS Identification of Δ9-Carboxy-Tetrahydrocannibinol in Urine with the Finnigan ITS40
- 1 September 1990
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Analytical Toxicology
- Vol. 14 (5) , 292-295
- https://doi.org/10.1093/jat/14.5.292
Abstract
The Finnigan MAT ITS40 GC/MS permits the accurate full mass spectral identification and reproducible quantitation of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (9-carboxy-THC) in urine. Positive identification of 9-carboxy-THC is based on full mass spectral cutoff criteria whose fit value is 900. The fit value is generated from a statistically significant correlation comparison of the targeted unknown against an authentic 9-carboxy-THC standard, whose mass spectrum has been generated on the ITS40. The limit of detection (LOD) and limit of quantitation (LOQ) are 2.5 ng/mL and 5 ng/mL, respectively, using 5 mL of urine. The quantitative linear dynamic range of the assay is greater than two orders of magnitude, ranging from 5 to 1,000 ng/mL.This publication has 0 references indexed in Scilit: