Selective Oxidation of 2-Bromo-m-xylene to 2-Bromo-3-methylbenzoic Acid or 2-Bromoisophthalic Acid
- 1 October 1986
- journal article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 59 (10) , 3285-3286
- https://doi.org/10.1246/bcsj.59.3285
Abstract
Aqueous sodium dichromate oxidation of 2-bromo-m-xylene (1) under a carbon dioxide pressure gave 2-bromoisophthalic acid (58%), while NBS-bromination of 1 followed by Sommelet oxidation to aldehyde and then potassium permanganate oxidation enabled the isolation of 2-bromo-3-methylbenzoic acid in 42% yield.This publication has 7 references indexed in Scilit:
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