Partially fluorinated heterocyclic compounds. Part VI. Some reactions of 4,5,6,7-tetrafluorobenzo[b]furan
- 1 January 1968
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society C: Organic
- p. 580-584
- https://doi.org/10.1039/j39680000580
Abstract
The reaction of 4,5,6,7-tetrafluorobenzo[b]furan (I) with sodium methoxide gave a mixture of the 4-, 6-, and 7-methoxytrifluorobenzo[b]furans in the ratio 27:57:16. 4,5,7-Trifluoro-6-methoxybenzo[b]furan was synthesised independently. Acetylation of (I) gave a mixture of the 2- and 3-acetyl derivatives in the ratio 85:15, and metallation of (I) with butyl-lithium gave the 2-lithio-compound which was converted into the 2-carboxylic acid and the 2-aldehyde.Keywords
This publication has 0 references indexed in Scilit: