Abstract
By means of a microinjection method it was possible to measure the fragility of mesenteric capillaries of the frog. Roentgen irradiation (3600 r and 7200 r), heparin injection, trypsin and peptone shock increase the fragility of the capillaries. The increased capillary fragility appears to be a consequence of a liberation of heparin into the circulation, due to the irradiation or shock treatments.