Abstract
Two distinct isolates of Staphylococcus aureus were obtained on several occasions from an infected squamous‐cell carcinoma of the lip on an elderly male patient. One isolate was methicillin‐resistant and the other methicillin‐sensitive, but both were phage type 88. Sensitivity to other antibiotics of the two isolates and of their penicillinase‐negative variants has been studied, as has also the effect of sodium chloride and incubation temperature on methicillin resistance and intrinsic resistance to benzylpenicillin. The origin and relationship of the two isolates are as yet unexplained.