Further Biochemical Studies of the Human B-Cell Differentiation Antigens B1 and B2
- 1 January 1983
- journal article
- research article
- Published by Mary Ann Liebert Inc in Hybridoma
- Vol. 2 (1) , 17-28
- https://doi.org/10.1089/hyb.1983.2.17
Abstract
Two human B lymphocyte-associated antigens, B1 and B2, were studied by immunoprecipitation using monoclonal antibodies. B1 was found to be a nonglycosylated protein of MW 35 kD, phosphorylated at serine and threonine. B2, a 140 kD MW antigen, was characterized as a glycoprotein without phosphorylated sites. Both proteins were found to contain portions which could be labeled with 125I-iodonaphthylazide. The B1 protein displayed hydrophobic properties whereas B2 had a more amphiphilic character.Keywords
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