BLOOD REGENERATION IN SEVERE ANEMIA

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Abstract
Beef marrow powder or cooked beef spleen are not especially potent food factors in promoting hemoglobin regeneration in severe anemia. Under controlled conditions there is an output of 20-50 gm. of hemoglobin per 2 weeks'' period due to 150-300 gm. of cooked spleen per day, over controls on standard bread. Bone marrow powder, 30-40 gm. daily, causes an increase of 20-25 gm. A part of the increase following spleen and marrow feeding is certainly due to the blood hemoglobin content. Brain tissue is a favorable diet factor for hemoglobin regeneration in severe anemia; 200-300 gm. of cooked brain per day causes an average increase of 20-25 gm. This response may be due in some measure to the high Fe content. An intake of 200-300 gm. of pancreas gives average increase of 35 gm. These reactions do not compare with the enormous increases during heavy feeding with liver or kidney. The question of organic versus inorganic Fe is discussed in the light of these experiments. The fundamental condition is an Fe shortage in the body; given such a deficit, due to prolonged anemia or other causes, the body can readily utilize either organic or inorganic Fe.

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