HIV resistance to reverse transcriptase inhibitors

This publication has 70 references indexed in Scilit:

• Bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships of novel substituted indole analogs and the identification of 1-[(5-methanesulfonamido-1H-indol-2-yl)carbonyl]-4-[3-[(1-methylethyl)amino]pyridinyl]piperazinemonomethanesulfonate (U-90152S), a second-generation clinical candidate
  Journal of Medicinal Chemistry, 1993
• Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine
  Antimicrobial Agents and Chemotherapy, 1993
• [2',5'-Bis-O-(tert-butyldimethylsilyl)]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) (TSAO) derivatives of purine and pyrimidinenucleosides as potent and selective inhibitors of human immunodeficiency virus type 1
  Antimicrobial Agents and Chemotherapy, 1992
• L-696,229 specifically inhibits human immunodeficiency virus type 1 reverse transcriptase and possesses antiviral activity in vitro
  Antimicrobial Agents and Chemotherapy, 1992
• HIV Inhibitors Targeted at the Reverse Transcriptase
  AIDS Research and Human Retroviruses, 1992
• Broad-spectrum anti-DNA virus and anti-retrovirus activity of phosphonylmethoxyalkylpurines and -pyrimidines
  Biochemical Pharmacology, 1991
• Inhibition of HIV-1 Replication by a Nonnucleoside Reverse Transcriptase Inhibitor
  Science, 1990
• Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives
  Nature, 1990
• Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative
  Biochemical and Biophysical Research Communications, 1989
• A novel lead for specific anti-HIV-1 agents: 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine
  Journal of Medicinal Chemistry, 1989