Teratogenic Effects of a Chelating Agent and Their Prevention by Zinc
- 2 July 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 173 (3991) , 62-64
- https://doi.org/10.1126/science.173.3991.62
Abstract
Ingestion of a chelating agent (ethylenediaminetetraacetic acid) by female rats during pregnancy impaired reproduction and resulted in congenitally malformed young. When ethylenediaminetetraacetic acid was fed from days 6 to 21 of gestation, all of the full-term young had gross congenital malformations. These effects were prevented by simultaneous supplementation with 1000 parts per million of dietary zinc.Keywords
This publication has 13 references indexed in Scilit:
- Teratogenic effects of short‐term and transitory zinc deficiency in ratsTeratology, 1971
- Lack of Mobilization of Bone and Liver Zinc under Teratogenic Conditions of Zinc Deficiency in RatsJournal of Nutrition, 1971
- The Improvement of Hatchability of Coturnix (J apanese Quail) Eggs by EDTAPoultry Science, 1970
- Zinc-Deficient Embryos: Reduced Thymidine IncorporationScience, 1969
- Plasma Zinc and Leukocyte Changes in Weanling and Pregnant Rats during Zinc DeficiencyExperimental Biology and Medicine, 1968
- Severe Zinc Deficiency in Male and Female RatsJournal of Nutrition, 1968
- Congenital Malformations Resulting from Zinc Deficiency in Rats.Experimental Biology and Medicine, 1966
- Antagonistic Relationship between Dietary Cadmium and ZincScience, 1963
- Production of Zinc Deficiency in Turkey Poults by Dietary Cadmium ,Poultry Science, 1961
- THE DESTRUCTIVE EFFECT OF CADMIUM ION ON TESTICULAR TISSUE AND ITS PREVENTION BY ZINCJournal of Endocrinology, 1957