Myelinated Nociceptive Afferents Account for the Hyperalgesia That Follows a Burn to the Hand
- 25 September 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 213 (4515) , 1527-1529
- https://doi.org/10.1126/science.7280675
Abstract
Monkeys and human subjects were exposed to a series of thermal stimuli before and after a 53 degrees C, 30-second burn to the glabrous skin of the hand. The responses of C- and A-fiber nociceptive afferents in the monkeys and subjective responses by the humans were compared. The burn resulted in increased sensitivity of the A fibers, decreased sensitivity of the C fibers, and increased pain sensibility (hyperalgesia) in the human subjects.This publication has 12 references indexed in Scilit:
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