Structure–activity and crystallographic analysis of a new class of non-amide-based thrombin inhibitor
- 1 January 2000
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 10 (1) , 79-82
- https://doi.org/10.1016/s0960-894x(99)00617-4
Abstract
No abstract availableKeywords
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- Structural Analysis of Thrombin Complexed with Potent Inhibitors Incorporating a Phenyl Group as a Peptide Mimetic and Aminopyridines as Guanidine SubstitutesJournal of Medicinal Chemistry, 1998
- Enzyme flexibility, solvent and ‘weak’ interactions characterize thrombin–ligand interactions: implications for drug designStructure, 1996