Minimal Bone Scan Findings in the Presence of Wide-Spread Osteobiastic Disease on Skeletal Radiography

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Abstract
A case of indolent carcinoma of the breast metastatic to bone is presented. Radiographic findings showed dramatic osteoblastic activity throughout the skeleton, but the bone scan was mildly abnormal in only one of these areas. A "superscan" appearance was excluded by a whole-body retention study.