PERIPHERAL NEUROPATHY

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Abstract
It is possible to reproduce the picture of peripheral neuropathy by temporarily interrupting the blood supply to an extremity.1 Sensory dissociation is a characteristic feature of both ischemic neuropathy and the peripheral neuropathy complicating alcoholism and other conditions associated with disturbed nutrition.2 Light touch, position and vibration senses are affected earlier and more severely, while pain sense appears to be relatively well preserved. Painful stimuli may, however, result in extremely unpleasant sensations. Such a sensation is best elicited by scraping the sole of the foot with an object such as a key, as in testing for the Babinski sign, and is experienced as "cutting" or "burning." This is an extremely unpleasant sensation, which in no way resembles tickling. Furthermore, this phenomenon does not occur in normal persons, and is invariably associated with defective sensation. For this reason, we have chosen to call it plantar dysesthesia, rather than hyperalgesia

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