Somatomedin B: Mitogenic Activity Derived from Contaminant Epidermal Growth Factor
- 4 September 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 213 (4512) , 1122-1123
- https://doi.org/10.1126/science.6973821
Abstract
The mitogenic effect of somatomedin B on human cultured glial cells was neutralized by the addition of antibodies to mouse epidermal growth factor. Somatomedin B contained epidermal growth factor--like activity, competing for binding to the epidermal growth factor receptor. It is concluded that contaminating epidermal growth factor may explain the entire mitogenic activity of somatomedin B.This publication has 10 references indexed in Scilit:
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