Inhibition of TGFβ signaling in cancer therapy

This publication has 53 references indexed in Scilit:

• Activated type I TGFβ receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression
  Oncogene, 2005
• Effect of Conditional Knockout of the Type II TGF-β Receptor Gene in Mammary Epithelia on Mammary Gland Development and Polyomavirus Middle T Antigen Induced Tumor Formation and Metastasis
  Cancer Research, 2005
• Conditional Overexpression of Active Transforming Growth Factor β1 In vivo Accelerates Metastases of Transgenic Mammary Tumors
  Cancer Research, 2004
• Smad-Binding Defective Mutant of Transforming Growth Factor β Type I Receptor Enhances Tumorigenesis but Suppresses Metastasis of Breast Cancer Cell Lines
  Cancer Research, 2004
• Increased Malignancy of Neu-Induced Mammary Tumors Overexpressing Active Transforming Growth Factor β1
  Molecular and Cellular Biology, 2003
• Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer
  Nature Reviews Cancer, 2003
• Transforming growth factor β signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis
  Proceedings of the National Academy of Sciences, 2003
• Targeting the TGFβ signaling network in human neoplasia
  Cancer Cell, 2003
• Metastasis is driven by sequential elevation of H-ras and Smad2 levels
  Nature Cell Biology, 2002
• Transforming growth factors: isolation of polypeptides from virally and chemically transformed cells by acid/ethanol extraction.
  Proceedings of the National Academy of Sciences, 1980