JAUNDICE ASSOCIATED WITH THE ADMINISTRATION OF SODIUM P-AMINOSALICYLIC ACID: REVIEW OF THE LITERATURE AND REPORT OF A CASE

Abstract
A case of hepatitis with clinical jaundice developing in a patient with miliary tuberculosis on PAS therapy is presented with autopsy findings. A review of the literature concerning the development of jaundice attributed to PAS therapy is presented, along with some of the clinical characteristics of this condition. It is suggested that the onset of fever and skin eruption in a patient on PAS therapy should arouse suspicion of drug toxicity and the drug be discontinued promptly.

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