Therapeutic myocardial angiogenesis using percutaneous intrapericardial drug delivery
Open Access
- 1 January 1999
- journal article
- research article
- Published by Wiley in Clinical Cardiology
- Vol. 22 (S1) , 6-9
- https://doi.org/10.1002/clc.4960221305
Abstract
In this manuscript, we describe the potential role of the pericardial space as a drug delivery reservoir to administer angiogenic agents to the heart resulting in functionally significant angiogenesis with single bolus basic fibroblast growth factor (bFGF) delivery. We also describe a percutaneous subxyphoid pericardial access technique that is safe, rapid, and reliable.Keywords
This publication has 27 references indexed in Scilit:
- Modulation of myocardial perfusion and vascular reactivity by pericardial basic fibroblast growth factor: Insight into ischemia-induced reduction in endothelium-dependent vasodilatationThe Journal of Thoracic and Cardiovascular Surgery, 1998
- Results of Intracoronary Recombinant Human Vascular Endothelial Growth Factor (rhVEGF) Administration TrialJournal of the American College of Cardiology, 1998
- Local Perivascular Basic Fibroblast Growth Factor (bFGF) Treatment in Patients With Ischemic Heart DiseaseJournal of the American College of Cardiology, 1998
- Effect of Basic Fibroblast Growth Factor on Myocardial Angiogenesis in Dogs With Mature Collateral VesselsJournal of the American College of Cardiology, 1997
- SHORT COMMUNICATION: Expression of FGF5 in choroidal neovascular membranes associated with ARMDCurrent Eye Research, 1997
- Intrapericardial basic fibroblast growth factor induces myocardial angiogenesis in a rabbit model of chronic ischemiaAmerican Heart Journal, 1995
- Intracoronary injection of basic fibroblast growth factor enhances angiogenesis in infarcted swine myocardiumJournal of the American College of Cardiology, 1993
- Expression of basic and acidic fibroblast growth factors and their receptor in normal and atherosclerotic human arteriesCardiovascular Research, 1993
- Importance of complete revascularization in performance of the coronary bypass operationThe American Journal of Cardiology, 1983
- Complete and incomplete revascularization at aortocoronary bypass surgery: Experience with 392 consecutive patientsAmerican Heart Journal, 1974