Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents — a case of imbalanced DNA repair
- 1 January 1995
- journal article
- Published by Elsevier in Mutation Research/DNA Repair
- Vol. 336 (1) , 9-17
- https://doi.org/10.1016/0921-8777(94)00035-5
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- 3T3 NIH murine fibroblasts and B78 murine melanoma cells expressing the Escherichia coli N3-methyladenine-DNA glycosylase I do not become resistant to alkylating agentsCarcinogenesis: Integrative Cancer Research, 1994
- Increased resistance of the Chinese hamster mutant irsl cells to monofunctional alkylating agents by transfection of the E. coli or mammalian N3-methyladenine-DNA-glycosylase genesMutation Research/DNA Repair, 1993
- Contribution of O6‐alkylguanine and N‐alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: New insights gained from studies of genetically engineered mammalian cell linesEnvironmental and Molecular Mutagenesis, 1993
- Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in Chinese hamster ovary cellsCarcinogenesis: Integrative Cancer Research, 1992
- Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agentsCarcinogenesis: Integrative Cancer Research, 1991
- Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agentsMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1990
- Apurinic sites as mutagenic intermediatesCell, 1985
- Adaptation to alkylation resistance involves the induction of a DNA glycosylaseNature, 1982
- Induction of a DNA glycosylase for N-methylated purines is part of the adaptive response to alkylating agentsNature, 1982
- On time dependency of frequency and distribution of chromatid aberrations induced by mutagens with delayed effects. An interpretationJournal of Theoretical Biology, 1981