Prediction of consanguinity using human DNA fingerprints.

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Abstract
DNA fingerprinting was performed to verify the pedigree structure of a family under investigation for an unusual case of .beta. thalassaemia. A higher than expected proportion of hypervariable bands was shared by the proband and his mother, leading to suspicion that the child had been the product of a consanguineous mating. Further analysis of the mother''s brother showed that he was almost certainly the proband''s father.