Loffler's Syndrome Associated with Nickel Sensitivity

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Abstract
The increasing prevalence of nickel sensitivity in recent years has been emphasized by many investigators.* Most of these investigators have directed attention primarily to the dermatologic manifestations of sensitization to nickel; however, it is noteworthy that other allergic phenomena may also be encountered. Within the past year Arvidsson and Bogg1 published a case report which indicated an association between Löffler's syndrome and acute nickel dermatitis. This publication has stimulated us to report a second case of Löffler's syndrome (pulmonary eosinophilia) in association -with severe nickel sensitivity. Report of Case The patient is a chemical engineer, aged 52 years, who was employed for several years in the design and development of an industrial plant manufacturing nickel carbonyl. The plant was constructed in a distant city in 1952, and during the first 6 months of the plant's operation, the patient was engaged in direct supervision of nickel carbonyl production. During these

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