High Performance Liquid Chromatography Assay for Piroxicam in Pharmaceutical Products
- 1 July 1987
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Chromatographic Science
- Vol. 25 (7) , 292-295
- https://doi.org/10.1093/chromsci/25.7.292
Abstract
A high performance liquid chromatographic assay for piroxicam in pharmaceutical preparations is described. The method uses a reversed-phase C18 column with pH 3 aqueous buffer/methanol, 55:45, v/v mobile phase, and is selective for piroxicam in the presence of other “oxicams,” synthetic precursors, by-products, degradation products, metabolites, and related compounds. Applications to capsules, tablets, ointments, suppositories, ophthalmic suspensions, and rodent feeds are cited.This publication has 1 reference indexed in Scilit:
- Synthesis and antiinflammatory activity of metabolites of piroxicamJournal of Medicinal Chemistry, 1981