Antimicrobial peptides from hylid and ranin frogs originated from a 150‐million‐year‐old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain
Open Access
- 11 April 2003
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 270 (9) , 2068-2081
- https://doi.org/10.1046/j.1432-1033.2003.03584.x
Abstract
The dermal glands of frogs produce antimicrobial peptides that protect the skin against noxious microorganisms and assist in wound repair. The sequences of these peptides are very dissimilar, both wi...Keywords
This publication has 68 references indexed in Scilit:
- Antimicrobial peptides of multicellular organismsNature, 2002
- Molecular Evidence for the Early History of Living AmphibiansMolecular Phylogenetics and Evolution, 1998
- Antimicrobial peptides from amphibian skin: What do they tell us?Biopolymers, 1998
- New caerin antibacterial peptides from the skin glands of the Australian tree frogLitoria xanthomeraJournal of Peptide Science, 1997
- Rapid evolution of immunoglobulin superfamily C2 domains expressed in immune system cellsMolecular Biology and Evolution, 1997
- Characterization and flow properties of lyotropic ultrahigh‐molar‐mass polysaccharide mesophasesMacromolecular Symposia, 1994
- Isolation and structure of novel defensive peptides from frog skinEuropean Journal of Biochemistry, 1994
- Novel antimicrobial peptides from skin secretion of the European frog Rana esculentaFEBS Letters, 1993
- Isolation, amino acid sequence and synthesis of dermaseptin, a novel antimicrobial peptide of amphibian skinBiochemistry, 1991
- A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequencesJournal of Molecular Evolution, 1980