Role of Members of the Vitamin B Complex in Enzyme Systems
Open Access
- 1 June 1946
- journal article
- research article
- Published by Cambridge University Press (CUP) in Proceedings of the Nutrition Society
- Vol. 4 (2) , 92-106
- https://doi.org/10.1079/pns19460022
Abstract
A review. Aneurin (thiamine) is intimately connected with the changes undergone by pyruvic acid in the living cell, which include decarboxylation, oxidation, dismutation, condensations and syntheses; it is also concerned in the oxidation of a-keto-glutarate and acetic acid. Nicotinamide is a constituent of the molecules of diphospho-nicotinamide-adenine-dinucleotide (coenzyme II) and the corresponding triphosphodinucleotide (cozymase.) Riboflavin occurs in the prosthetic group (flavin -adenine-dinucleotide) of the flavoproteins which are concerned in a variety of cellular dehydrogenations. Pyridoxin is closely concerned with amino acid decarboxylations and transamina-tions, and d-pantothenic acid apparently with carbohydrate metabolism. 130 references.Keywords
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