CLINICAL AND ROENTGENOGRAPHIC FEATURES OF NOSOCOMIAL PULMONARY-DISEASE DUE TO MYCOBACTERIUM-XENOPI

Publisher Website
Google Scholar
Abstract
Nineteen cases of pulmonary disease due to M. xenopi, a nosocomial infection related to the hospital water system, were described. Pre-existing lung disease and prolonged environmental exposure during previous hospitalizations were apparent predisposing factors. Twelve patients had respiratory symptoms, including 3 with hemoptysis; at the time an abnormal chest roentgenogram was obtained. The predominant radiographic presentation of lung diseases caused by M. xenopi was a nodular or mass shadow, but cavitary disease and multiple nodular densities were frequently observed. One subject had a solitary pulmonary nodule, and surgical resection was performed. In 12 patients who were skin tested with both M. xenopi sensitin and PPD[purified protein derivative]-tuberculin, induration was consistently greater with M. xenopi. Initial isolates of M. xenopi were uniformly sensitive in vitro to 2.0 .mu.g streptomycin, 1.0 .mu.g isoniazid and 10.0 .mu.g p-aminosalicylic acid. In general, disease due to M. xenopi was successfully treated with standard antituberculosis drugs.

This publication has 2 references indexed in Scilit: