Allergic contact dermatitis from a novel diamino intermediate, 5‐[(2‐aminoethyl)thiomethyl]‐N,N‐dimethyl‐2‐furanmethanamine, in laboratory synthesis
- 1 December 1983
- journal article
- research article
- Published by Wiley in Contact Dermatitis
- Vol. 9 (6) , 456-458
- https://doi.org/10.1111/j.1600-0536.1983.tb04463.x
Abstract
Allergic contact sensitivity to 5-[(2-aminoethyl)thiomethyl]-N,N-dimethyl-2-furanmethanamine, a diamino intermediate in the synthesis of a novel H2 antagonist, Ranitidine, is reported in an industrial chemist with hand dermatitis, who was working for a prolonged period on the conversion of this intermediate to its fumarate salt.Keywords
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