Studies on Peptides. VIII. Synthesis of Two Heptapeptides Isolated from Pituitary Glands

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Abstract
Two heptapeptides, phenylalanylarginyltryptophylglycylserylprolylproline (I) and phenylalanylarginyltryptopylglycyllysylprolylvaline amide (II) have been synthesized. It was found that neither exhibited in vitro melanotropic activity in contrast to the observations reported on native I and II isolated form porcine pituitary glands.