Cleavage of eIF4G by HIV‐1 protease: effects on translation
Open Access
- 4 December 2002
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 533 (1) , 89-94
- https://doi.org/10.1016/s0014-5793(02)03764-x
Abstract
We have recently reported that HIV‐1 protease (PR) cleaves the initiation factor of translation eIF4GI [Ventoso et al., Proc. Natl. Acad. Sci. USA 98 (2001) 12966–12971]. Here, we analyze the proteol...Keywords
This publication has 34 references indexed in Scilit:
- In Vitro Cleavage of eIF4GI but not eIF4GII by HIV-1 Protease and its Effects on Translation in the Rabbit Reticulocyte Lysate SystemJournal of Molecular Biology, 2002
- HIV-1 protease cleaves eukaryotic initiation factor 4G and inhibits cap-dependent translationProceedings of the National Academy of Sciences, 2001
- Molecular mechanisms of translation initiation in eukaryotesProceedings of the National Academy of Sciences, 2001
- Mutually Cooperative Binding of Eukaryotic Translation Initiation Factor (eIF) 3 and eIF4A to Human eIF4G-1Journal of Biological Chemistry, 2000
- Translation initiation factor modifications and the regulation of protein synthesis in apoptotic cellsCell Death & Differentiation, 2000
- eIF4 Initiation Factors: Effectors of mRNA Recruitment to Ribosomes and Regulators of TranslationAnnual Review of Biochemistry, 1999
- Cleavage of p220 by Purified Poliovirus 2Apro in Cell-Free Systems: Effects on Translation of Capped and Uncapped mRNAsBiochemistry, 1997
- Initiation of Protein Synthesis in Eukaryotic CellsEuropean Journal of Biochemistry, 1996
- Mapping of Functional Domains in Eukaryotic Protein Synthesis Initiation Factor 4G (eIF4G) with Picornaviral ProteasesJournal of Biological Chemistry, 1995
- Proteolytic cleavage of initiation factor elF-4γ in the reticulocyte lysate inhibits translation of capped mRNAs but enhances that of uncapped mRNAsNucleic Acids Research, 1995