Reactive arthritis and Reiter’s syndrome-the clinical spectrum

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Abstract
Reactive arthropathy and Reiter’s syndrome are two terms that are used more or less interchangeably. The latter defines a triad or more of features, while the former relates to the inflammatory joint process and relationship to infection. In theory, reactive arthropathy may be defined as an inflammatory arthropathy distant in time and place from the original inciting infection, which is usually in the bowel or genitourinary tract. More recently, we have come to suspect that respiratory organisms can also precipitate disease and, of more importance, we accept that the synovial joint is not free of bacterial insult. As discussed elsewhere, there is growing evidence that fragments of organisms and antigenic determinants are found within the joint cavity or synovial tissues. The importance of this phenomenon and the relationship to potential antibiotic therapy remains unclear but of paramount interest and importance.

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