Disseminated herpesvirus infection. Association with primary genital herpes in pregnancy

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Abstract
A patient with primary herpes simplex virus (HSV) type 2 genital infection had dissemination in the 37th wk of her 1st pregnancy. This was manifested by severe hepatitis, pancreatis and genital lesions. Temporary improvement followed the delivery of a healthy infant by cesarean section. Encephalitis became evident on the 3rd postpartum day, and recovery was complicated by profound bradycardia, possibly due to viral myocarditis. Vidarabine was administered for 7 days, and the patient survived with only mild neurologic sequellae. This is the 4th reported case of disseminated herpesvirus infection in pregnancy and the 1st due to HSV type 2. Pregnancy must be considered as a possible predisposing factor in dissemination of primary HSV infection.

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