Nuclear resonant scattering of gamma rays-a new technique for in vivo measurement of body iron stores

1 July 1979

journal article
research article
Published by IOP Publishing in Physics in Medicine & Biology

Vol. 24 (4) , 689-701
https://doi.org/10.1088/0031-9155/24/4/001

Abstract

A technique for the measurement of body Fe utilizing nuclear resonant scattering of .gamma. rays was developed. Photons (847 keV) emitted from a gaseous 56MnCl2 source are resonantly scattered from 56Fe present in the body. Measurement is made using large volume Ge(Li) detectors. The spatial uniformity of activation, the sensitivity of the detection system and the limits of detection were investigated. Measurements were made on a liver phantom. The resonance scattering technique permits determination of normal levels of Fe in the liver with a radiation dose of 2 rem. This method may be useful to evaluate Fe overload in humans.

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