The interaction of glutathione with 4-hydroxycyclophosphamide and phosphoramide mustard, studied by 31P nuclear magnetic resonance spectroscopy
- 1 December 1994
- journal article
- Published by Elsevier in Chemico-Biological Interactions
- Vol. 93 (3) , 185-196
- https://doi.org/10.1016/0009-2797(94)90019-1
Abstract
No abstract availableKeywords
This publication has 11 references indexed in Scilit:
- Glutathione S-transferase in chemotherapy resistance and in carcinogenesisBiochemistry and Cell Biology, 1992
- The role of glutathione-dependent enzymes in drug resistancePharmacology & Therapeutics, 1991
- Historical aspects of glutathione and cancer chemotherapyPharmacology & Therapeutics, 1991
- Glutathione diminishes the anti-tumour activity of 4-hydroperoxycyclophosphamide by stabilising its spontaneous breakdown to alkylating metabolitesBritish Journal of Cancer, 1991
- Phosphorus-31 NMR studies of the kinetics of bisalkylation by isophosphoramide mustard: comparisons with phosphoramide mustardJournal of Medicinal Chemistry, 1989
- Activation mechanisms of mafosfamide and the role of thiols in cyclophosphamide metabolismJournal of Medicinal Chemistry, 1987
- NMR spectroscopic studies of intermediary metabolites of cyclophosphamide. A comprehensive kinetic analysis of the interconversion of cis- and trans-4-hydroxycyclophosphamide with aldophosphamide and the concomitant partitioning of aldophosphamide between irreversible fragmentation and reversible conjugation pathwaysJournal of Medicinal Chemistry, 1984
- Phosphorus-31 NMR kinetic studies of the intra- and intermolecular alkylation chemistry of phosphoramide mustard and cognate N-phosphorylated derivatives of N,N-bis(2-chloroethyl)amineJournal of Medicinal Chemistry, 1982
- Synthesis and preliminary antitumor evaluation of 4-(SR)-sulfido-cyclophosphamidesCancer Chemotherapy and Pharmacology, 1979
- The problem of specificity and selectivity of alkylating cytostatics; studies on N-2-chloroethylamido-oxazaphosphorinesZeitschrift für Krebsforschung und Klinische Onkologie, 1977