Highly Efficient Ruthenium Catalysts for the Formation of Tetrasubstituted Olefins via Ring-Closing Metathesis
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- 23 March 2007
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 9 (8) , 1589-1592
- https://doi.org/10.1021/ol0705144
Abstract
A series of ruthenium-based metathesis catalysts with N-heterocyclic carbene (NHC) ligands have been prepared in which the N-aryl groups have been changed from mesityl to mono-ortho-substituted phenyl (e.g., tolyl). These new catalysts offer an exceptional increase in activity for the formation of tetrasubstituted olefins via ring-closing metathesis (RCM), while maintaining high levels of activity in ring-closing metathesis (RCM) reactions that generate di- and trisubstituted olefins.Keywords
This publication has 17 references indexed in Scilit:
- A Standard System of Characterization for Olefin Metathesis CatalystsOrganometallics, 2006
- Multiple Metal–Carbon Bonds for Catalytic Metathesis Reactions (Nobel Lecture)Angewandte Chemie International Edition in English, 2006
- Olefin Metathesis: The Early Days (Nobel Lecture)Angewandte Chemie International Edition in English, 2006
- Olefin‐Metathesis Catalysts for the Preparation of Molecules and Materials (Nobel Lecture)Angewandte Chemie International Edition in English, 2006
- Nitro-Substituted Hoveyda−Grubbs Ruthenium Carbenes: Enhancement of Catalyst Activity through Electronic ActivationJournal of the American Chemical Society, 2004
- Recent Methods for the Synthesis of (E)‐Alkene Units in Macrocyclic Natural ProductsAngewandte Chemie International Edition in English, 2003
- Efficient and Recyclable Monomeric and Dendritic Ru-Based Metathesis CatalystsJournal of the American Chemical Society, 2000
- Ruthenium carbene complexes with imidazolin-2-ylidene ligands allow the formation of tetrasubstituted cycloalkenes by RCMTetrahedron Letters, 1999
- A Recyclable Ru-Based Metathesis CatalystJournal of the American Chemical Society, 1999
- Recent advances in olefin metathesis and its application in organic synthesisTetrahedron, 1998