OCCUPATIONAL FACTORS IN THE EPIDEMIOLOGY OF LEUKEMIA IN HIROSHIMA AND NAGASAKI1

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Abstract
Ishimaru, T. (Dept. Statistics, Atomic Bomb Casualty Commission, U.S. Marine Corps Air Station, FPO Seattle, Washington 98764), H. Okada, T. Tomiyasu, T. Tsuchimoto, T. Hoshino and M. Ichimaru. Occupational factors in the epidemiology of leukemia in Hiroshima and Nagasaki. Amer J Epidem 93: 157–165, 1971.—This epidemiologic study examined retrospectively occupational and other environmental factors in relation to the incidence of leukemia. A total of 492 cases of leukemia with onset in 1945–1967 in Hiroshima or Nagasaki City, Japan, and controls, were selected from the Atomic Bomb Casualty Commission Leukemia Registry and interviewed during the period 1966–1969. In 303 pairs of adult leukemia cases and controls the risk was approximately 2.5 times higher among those with history of probable cccupational exposure to benzene or its derivatives and medical x-ray. The change in relative risk of leukemia due to the coexistence of the two factors (radiation and occupation) was also examined.

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