Tuberous Sclerosis

Publisher Website
Google Scholar
Abstract
Tuberous sclerosis is a disease entity with protean manifestations, reported as being present in every organ and almost every structure of the body. It is familial and hereditary. The skin lesions are not primarily problems of skin therapy. Gratification must be derived from making a diagnosis in the incomplete or forme fruste case in practice, without the classical triad of mental deficiency, epilepsy, and adenoma sebaceum. It is this type of case in which recommendations regarding marriage and reproduction are especially important in a condition unfamiliar to most physicians. Historically the names of von Recklinghausen,1who first described brain and heart lesions; Bourneville,2who elaborated the brain findings; Pringle,3whose name is attached to the facial lesions; Hallopeau-Leredde,4who first described shagreen patches on the back; Sherlock,5who coined the term ``epiloia,'' and Van der Hoeve,6who first described the eye findings are all

This publication has 0 references indexed in Scilit: